承担儿童血液病临床诊断综合治疗工作，研究方向为儿童白血病发病机制、化疗耐药机制机制及免疫治疗。

曾慧敏，北京协和医学院医学博士，北京大学人民医院儿科副主任医师、副教授、硕士生导师，美国辛辛那提儿童医院访问学者,现担任儿科学科助理及儿科科研秘书。主持国家自然科学基金两项、北京大学人民医院卓越青年项目一项。第一或通讯作者发表论文在Nature Genetics、Ital J Pediatr、 Int J Lab Hematol等10余篇。中华医学会儿科分会肿瘤专业学组成员，北京妇幼保健与优生优育协会儿童早期综合发展学组成员。《Italian Journal of Pediatrics》《临床儿科杂志》《中国药学杂志》审稿专家。

主持国家自然科学基金两项、北京大学人民医院卓越青年项目一项、器官再生与智造全国重点实验室开放课题一项。

1.Wang Y, Xue YJ, Zuo YX, Jia YP, Lu AD, Zeng HM, Zhang LP. Treatment and outcomes of patients with B-ALL relapse after CD19 CAR-T therapy. J Transl Med. 2024 Jul 26;22(1):680.

2.Yu-Juan Xue, Yu Wang, Le-Ping Zhang, Ai-Dong Lu, Yue-Ping Jia , Ying-Xi Zuo, Hui-Min Zeng. Prognostic significance of Wilms' tumor gene 1 expression in children with B-cell precursor acute lymphoblastic leukemia.Front Oncol. 2024 Jan 15:13:1297870.

3.Yu Wang, Yu-Juan Xue, Ying-Xi Zuo, Yue-Ping Jia, Ai-Dong Lu, Hui-Min Zeng, Le-Ping Zhang. CD19-specific CAR-T Cell Treatment of 115 Children and Young Adults with Acute B Lymphoblastic Leukemia: Long-Term Follow-up. Cancer Res Treat. 2024 Jul;56(3):945-955.

4.Qianwen Shang, Yu Wang , Aidong Lu , Yueping Jia , Yingxi Zuo, Huimin Zeng, Leping Zhang . Impact of pre-infusion disease burden on outcomes in pediatric relapsed/refractory B-cell lymphoblastic leukemia following anti-CD19 CAR T-cell therapy.Leuk Lymphoma. 2025 Jan;66(1):54-63.

5.Qi Ma, Long Hu, Yingwan Luo, Miao Wang, Shui Yu, Aidong Lu, Leping Zhang, Huimin Zeng. Identification of apoptosis-related key genes and the associated regulation mechanism in thoracic aortic aneurysm. BMC Cardiovasc Disord. 2023 Sep 28;23(1):481.

6.Yu-Juan Xue, Yu Wang, Hui-Min Zeng , Le-Ping Zhang, et al. Clinical Analysis of Pediatric T-Cell Acute Lymphoblastic Leukemia Using the MRD-Oriented Strategy System. Clin Lymphoma Myeloma Leuk. 2023 Jul;23(7):477-483. 

7.Huimin Zeng,Guanhua Hu,Aidong Lu,Yueping Jia,Yingxi Zuo, Leping Zhang. Predictive impact of residual disease detected using multiparametric flow cytometry on risk stratification of paediatric acute myeloid leukaemia with normal karyotype. Int J Lab Hematol. 2021. Aug;43(4):752-759.

8.Wang Yu, Zeng Huimin, Zhang Leping, et al. The gene expression level of m6A catalytic enzymes is increased in ETV6/RUNX1-positive acute lymphoblastic leukemia. Int J Lab Hematol, 2021 Apr;43(2):e89-e91.

9.Yu Wang, Huimin Zeng, Leping Zhang. ETV6/RUNX1-positive childhood acute lymphoblastic leukemia in China: excellent prognosis with improved BFM protocol. 2018. Ital J Pediatr. 2018,44(1):94:541-546.

10.Xiaofan Zhu, Fuhong He, HuiminZeng, Shaoping Ling, Aili Chen, Gang Huang, Tao Cheng, Qian-fei Wang，et al. Identification of functional cooperative mutations of SETD2 in human acute leukemia. Nature Genetics. 2014,46(3):287-293.

11.尚倩雯 张乐萍 曾慧敏等.改良CLAG方案治疗儿童复发/难治急性髓系白血病的疗效和安全性. 临床儿科杂志，2024，42（07），594-599.

12.曾慧敏 胡冠华 陆爱东 贾月萍 左英熹 吴珺 张乐萍. 诱导化疗后骨髓缓解程度对儿童核心结合因子相关性急性髓系白血病预后的影响.中华实验血液学杂志.2021. 29(1),56-61.

(其他作者)

1.Yingwan Luo, Xiaomin Feng, Wei Lang, Weihong Xu, Wei Wang, Chen Mei, Li Ye, Shuanghong Zhu, Lu Wang, Xinping Zhou, Huimin Zeng, Liya Ma, Yanling Ren, Jie Jin, Rongzhen Xu, Gang Huang, Hongyan Tong. Ectopic expression of the transcription factor ONECUT3 drives a complex karyotype in myelodysplastic syndromes. J Clin Invest. 2024 Feb 22;134(8):e172468.

2.Yuting Tang, Qian Xu, Liang Hu, Xiaomei Yan, Xiaomin Feng, Asumi Yokota, Weinan Wang, Di Zhan, Durga Krishnamurthy, David E Ochayon, Lijun Wen, Li Huo, Huimin Zeng, Yingwan Luo, L Frank Huang, Mark Wunderlich, Jiwang Zhang, Eric Vivier, Jianfeng Zhou, Stephen N Waggoner, Gang Huang. Tumor Microenvironment-Derived R-spondins Enhance Anti-Tumor Immunity to Suppress Tumor Growth and Sensitize for Immune Checkpoint Blockade Therapy. Cancer Discov. 2021 Dec 1;11(12):3142-3157.

3.Riguo Fang , Jingliao Zhang, Huihui Yang, Jia Shi, Huimin Zeng, Xiaofan Zhu, Dong Wei , Pengfei Yuan, Tao Cheng, Yingchi Zhang. Highly efficient gene editing and single cell analysis of hematopoietic stem/progenitor cells from X-linked sideroblastic anemia patients. Signal Transduct Target Ther. 2021 Jul 2;6(1):248.